entity

SYSTEM XC-

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYSTEM XC-: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections
0Hypotheses
1Analyses
6Outgoing
8Incoming
0Experiments
1Debates

No AI portrait yet

Outgoing (6)

TargetRelationTypeStr
h-5d100034associated_withhypothesis1.00
Cysteine Importmediatesmechanism0.90
Ferroptosisregulatesprocess0.85
Cystineinteracts_withcompound0.85
FERROPTOSISinhibitsprocess0.80

Incoming (8)

SourceRelationTypeStr
h-5d100034targetshypothesis1.00
Erastininhibitscompound0.90
Sorafenibinhibitsdrug0.90
BECN1inhibitsprotein0.90
AMPKinhibitsprotein0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Ferroptosis in ALS and motor neuron disease: GPX4, lipid peroxidation, and iron

neurodegeneration | 2026-04-16 | 7 hypotheses Top: 0.680

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

Ferroptosis in ALS and motor neuron disease: GPX4, lipid peroxidation, and iron

closed · Rounds: 5 · Score: 0.59 · 2026-04-16

Related Research

Hypotheses and analyses mentioning SYSTEM XC- in their description or question text

No additional research found