Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about STRAP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | STRAP |
| Full Name | Serine Threonine Kinase Receptor Associated Protein |
| Chromosome | 15q24.1 |
| Function | The STRAP gene encodes a protein involved in RNA processing and splicing mechanisms critical for neuronal function and survival. |
| Primary Expression | various brain regions, including the cortex, hippocampus, and spinal cord, where it supports pr |
| UniProt ID | Q9Y2X9 |
| Ensembl ID | ENSG00000175206 |
| GeneCards | STRAP |
| Human Protein Atlas | STRAP |
| Associated Diseases | neurodegeneration |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
STRAP["STRAP"]
STRAP -->|"expressed in"| Als["Als"]
STRAP -->|"expressed in"| Neurodegeneration["Neurodegeneration"]
STRAP -->|"expressed in"| ALS["ALS"]
STRAP -->|"expressed in"| AND["AND"]
STRAP -->|"expressed in"| RAS["RAS"]
STRAP -->|"expressed in"| KCNJ6["KCNJ6"]
STRAP -->|"expressed in"| SPTLC1["SPTLC1"]
STRAP -->|"expressed in"| Hippocampus["Hippocampus"]
SPTLC1 -->|"expressed in"| STRAP
KCNJ6 -->|"expressed in"| STRAP
NEURODEGENERATION["NEURODEGENERATION"] -->|"expressed in"| STRAP
GENES["GENES"] -->|"expressed in"| STRAP| Target | Relation | Type | Str |
|---|---|---|---|
| Neurodegeneration | expressed_in | disease | 0.65 |
| Als | expressed_in | disease | 0.65 |
| ALS | expressed_in | disease | 0.65 |
| RAS | expressed_in | gene | 0.60 |
| JAG2 | associated_with | gene | 0.60 |
| KCNJ6 | expressed_in | gene | 0.60 |
| SPTLC1 | expressed_in | gene | 0.60 |
| Hippocampus | expressed_in | brain_region | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| JAG2 | associated_with | gene | 0.60 |
| SPTLC1 | expressed_in | gene | 0.60 |
| KCNJ6 | expressed_in | gene | 0.60 |
| NEURODEGENERATION | expressed_in | gene | 0.60 |
| GENES | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning STRAP in their description or question text
No additional research found