gene

SLC22A5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC22A5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

11Outgoing

5Incoming

0Experiments

0Debates

Summary

SLC22A5 is a gene implicated in neurodegeneration research. Key relationships include: expressed in, associated with, implicated in. Associated with Cancer, Carcinoma, Inflammation. Connected to 17 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	SLC22A5
Full Name	Solute Carrier Family 22 Member 5 (OCTN2)
Chromosome	5q31.1
Protein Type	Transporter
Function	encodes a 557-amino acid protein with a molecular weight of approximately 63 kDa.
Molecular Weight	63 kDa
Amino Acids	557 aa
Exons	11
UniProt ID	O76076
NCBI Gene ID	6583
Ensembl ID	ENSG00000197355
OMIM	604377
GeneCards	SLC22A5
Human Protein Atlas	SLC22A5
Associated Diseases	neurodegeneration
KG Connections	16 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC22A5 — AlphaFold O76076 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

slc22a5

gene · 2245 words

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Pathway Diagram

graph TD
    SLC22A5["SLC22A5"]
    Ms{"Ms"}
    SLC22A5 -->|"expressed in"| Ms
    Inflammation{"Inflammation"}
    SLC22A5 -->|"expressed in"| Inflammation
    Cancer{"Cancer"}
    SLC22A5 -->|"expressed in"| Cancer
    Carcinoma{"Carcinoma"}
    SLC22A5 -->|"expressed in"| Carcinoma
    INFLAMMATION["INFLAMMATION"]
    SLC22A5 -->|"expressed in"| INFLAMMATION
    PDGFRB["PDGFRB"]
    SLC22A5 -->|"associated with"| PDGFRB
    LEF1["LEF1"]
    SLC22A5 -->|"associated with"| LEF1
    CCR7["CCR7"]
    SLC22A5 -->|"associated with"| CCR7
    Immune_Response(["Immune Response"])
    SLC22A5 -->|"expressed in"| Immune_Response
    CANCER["CANCER"]
    SLC22A5 -->|"expressed in"| CANCER
    ABCG2["ABCG2"]
    SLC22A5 -->|"expressed in"| ABCG2
    neurodegeneration["neurodegeneration"]
    SLC22A5 -->|"implicated in"| neurodegeneration
    SLC22A4["SLC22A4"]
    SLC22A4 -->|"associated with"| SLC22A5
    ABCD3["ABCD3"]
    ABCD3 -->|"expressed in"| SLC22A5
    ABCA2["ABCA2"]
    ABCA2 -->|"expressed in"| SLC22A5
    ATP7A["ATP7A"]
    ATP7A -->|"expressed in"| SLC22A5
    ABCG1["ABCG1"]
    ABCG1 -->|"expressed in"| SLC22A5
    style SLC22A5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (11)

Target	Relation	Type	Str
Carcinoma	expressed_in	disease	0.65
Ms	expressed_in	disease	0.65
Inflammation	expressed_in	disease	0.65
Cancer	expressed_in	disease	0.65
LEF1	associated_with	gene	0.60
INFLAMMATION	expressed_in	gene	0.60
CCR7	associated_with	gene	0.60
Immune Response	expressed_in	pathway	0.60
CANCER	expressed_in	gene	0.60
PDGFRB	associated_with	gene	0.60
ABCG2	expressed_in	gene	0.60

Incoming (5)

Source	Relation	Type	Str
SLC22A4	associated_with	gene	0.60
ABCD3	expressed_in	gene	0.60
ABCA2	expressed_in	gene	0.60
ATP7A	expressed_in	gene	0.60
ABCG1	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLC22A5 in their description or question text

No additional research found