concept

PFKM

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PFKM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

11Outgoing

3Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PFKM
Key Genes/Proteins	PRMT1
Related Pathways	autophagy pathway, Glycolysis, Pentose Phosphate Pathway, WNT, Wnt signaling

Pathway Diagram

graph TD
    PFKM[PFKM]
    PFKM -->|regulates| Skeletal_Muscle_Differentiatio[Skeletal Muscle Differentiation]
    PFKM -->|promotes| Glycolysis[Glycolysis]
    PFKM -->|involved_in| Microautophagy[Microautophagy]
    PFKM -->|promotes| Myofibres_Differentiation[Myofibres Differentiation]
    PFKM -->|involved_in| Lysosomal_Degradation[Lysosomal Degradation]
    PFKM -->|suppresses| Pentose_Phosphate_Pathway[Pentose Phosphate Pathway]
    PFKM -->|expressed in| Muscle_Stem_Cells[Muscle Stem Cells]
    PFKM -->|activates| PRMT1[PRMT1]
    PFKM -->|expressed in| stem_cells[stem cells]
    PFKM -->|participates in| autophagy_pathway[autophagy pathway]
    Microautophagy -->|degrades| PFKM
    WNT[WNT] -->|downregulates| PFKM
    PRMT1 -->|phosphorylates| PFKM

Outgoing (11)

Target	Relation	Type	Str
Glycolysis	promotes	pathway	0.95
Skeletal Muscle Differentiation	regulates	process	0.95
Microautophagy	involved_in	process	0.90
Myofibres Differentiation	promotes	process	0.90
Lysosomal Degradation	involved_in	process	0.90
Pentose Phosphate Pathway	suppresses	pathway	0.85
Muscle Stem Cells	expressed_in	cell_type	0.85
stem cells	expressed_in	cell_type	0.60
autophagy pathway	participates_in	pathway	0.60
Wnt signaling	participates_in	pathway	0.60
PRMT1	activates	gene	0.60

Incoming (3)

Source	Relation	Type	Str
WNT	downregulates	pathway	0.90
Microautophagy	degrades	process	0.90
PRMT1	phosphorylates	gene	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PFKM in their description or question text

No additional research found