concept

MIR-369-3P

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR-369-3P: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections

0Hypotheses

0Analyses

34Outgoing

8Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	MIR-369-3P
Key Genes/Proteins	AND, IL-1Β, IL-6, INFLAMMATION, Interleukin, LDLR
Related Diseases	Als, ALS, Atherosclerosis, Diabetes, Inflammation
Related Pathways	Inflammasome, Inflammasome Signalling

Pathway Diagram

graph TD
    MIR_369_3P["MIR-369-3P"]
    MIR_369_3P -.protects against.-> Diabetes_Associated_Atheroscle["Diabetes-Associated Atherosclerosis"]
    MIR_369_3P -->|"targets"| GPR91["GPR91"]
    MIR_369_3P -->|"inhibits"| Succinate_GPR91_Signalling["Succinate-GPR91 Signalling"]
    MIR_369_3P -->|"inhibits"| Inflammasome_Signalling["Inflammasome Signalling"]
    MIR_369_3P -->|"expressed in"| Macrophage["Macrophage"]
    MIR_369_3P -->|"downregulates"| IL_1_["IL-1Beta"]
    MIR_369_3P -->|"downregulates"| TNF__["TNF-Alpha"]
    oxLDL["oxLDL"] -->|"downregulates"| MIR_369_3P
    INFLAMMATION["INFLAMMATION"] -->|"inhibits"| MIR_369_3P
    TNF["TNF"] -->|"inhibits"| MIR_369_3P
    IL_6["IL-6"] -->|"inhibits"| MIR_369_3P
    LDLR["LDLR"] -->|"inhibits"| MIR_369_3P
    RNA["RNA"] -->|"activates"| MIR_369_3P
    AND["AND"] -->|"inhibits"| MIR_369_3P

Outgoing (34)

Target	Relation	Type	Str
GPR91	targets	receptor	0.95
GPR91	targets	receptor	0.95
Diabetes-Associated Atherosclerosis	protects_against	disease	0.95
Succinate-GPR91 Signalling	inhibits	pathway	0.92
IL-1Β	downregulates	protein	0.90
TNF-Α	downregulates	protein	0.90
IL-6	downregulates	protein	0.90
Inflammasome Activation	inhibits	process	0.90
Inflammasome Signalling	inhibits	pathway	0.90
Macrophage	expressed_in	cell_type	0.90
IL-6	downregulates	protein	0.85
Macrophage Immunometabolism	regulates	process	0.85
Succinate	downregulates	compound	0.85
IL-1Β	downregulates	protein	0.85
TNF-Α	downregulates	protein	0.85
Macrophage Efferocytosis	upregulates	process	0.80
ATG10	inhibits	gene	0.70
Atherosclerosis	inhibits	disease	0.65
ALS	inhibits	disease	0.65
Als	inhibits	disease	0.65
Inflammation	inhibits	disease	0.65
Diabetes	inhibits	disease	0.65
Inflammasome	activates	pathway	0.60
TNF-Α	inhibits	gene	0.60
MICRORNAS	inhibits	gene	0.60
IL-6	inhibits	gene	0.60
Macrophage	inhibits	cell_type	0.60
Monocyte	inhibits	cell_type	0.60
AND	inhibits	gene	0.60
TNF	inhibits	gene	0.60
LDLR	inhibits	gene	0.60
INFLAMMATION	inhibits	gene	0.60
RNA	activates	gene	0.60
Interleukin	inhibits	protein	0.60

Incoming (8)

Source	Relation	Type	Str
oxLDL	downregulates	compound	0.90
oxLDL	downregulates	compound	0.85
INFLAMMATION	inhibits	gene	0.60
TNF	inhibits	gene	0.60
IL-6	inhibits	gene	0.60
LDLR	inhibits	gene	0.60
RNA	activates	gene	0.60
MICRORNAS	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIR-369-3P in their description or question text

No additional research found