gene

KDM5D

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KDM5D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

8Outgoing

4Incoming

0Experiments

0Debates

Summary

KDM5D is a gene implicated in neurodegeneration research. Key relationships include: associated with, interacts with, implicated in. Associated with Aging, Ms. Connected to 13 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	KDM5D
Full Name	Lysine Demethylase 5D
Chromosome	Yq11.223 (Y chromosome)
Primary Expression	testis and has been studied most extensively in the context of male germ cell development and cancer
Molecular Weight	175 kDa
Amino Acids	1560 aa
UniProt ID	Q9Y2T7
NCBI Gene ID	56843
Ensembl ID	ENSG00000125675
OMIM	426000024
GeneCards	KDM5D
Human Protein Atlas	KDM5D
Associated Diseases	Ms
Interactions	AGING, EXERCISE, JAK2, SCFD1
KG Connections	12 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KDM5D — AlphaFold Q9Y2T7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KDM5D Gene

gene · 1765 words

→

KDM5D Protein

protein · 635 words

→

Pathway Diagram

graph TD
    KDM5D["KDM5D"]
    Aging{"Aging"}
    KDM5D -->|"interacts with"| Aging
    Ms{"Ms"}
    KDM5D -->|"associated with"| Ms
    APOPTOSIS["APOPTOSIS"]
    KDM5D -->|"associated with"| APOPTOSIS
    FOXO1["FOXO1"]
    KDM5D -->|"associated with"| FOXO1
    EXERCISE["EXERCISE"]
    KDM5D -->|"interacts with"| EXERCISE
    Apoptosis(["Apoptosis"])
    KDM5D -->|"associated with"| Apoptosis
    Akt(["Akt"])
    KDM5D -->|"associated with"| Akt
    Immune_Response(["Immune Response"])
    KDM5D -->|"associated with"| Immune_Response
    neurodegeneration["neurodegeneration"]
    KDM5D -->|"implicated in"| neurodegeneration
    AGING["AGING"]
    AGING -->|"interacts with"| KDM5D
    SCFD1["SCFD1"]
    SCFD1 -->|"interacts with"| KDM5D
    JAK2["JAK2"]
    JAK2 -->|"interacts with"| KDM5D
    AKT["AKT"]
    AKT -->|"associated with"| KDM5D
    style KDM5D fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (8)

Target	Relation	Type	Str
Ms	associated_with	disease	0.65
Aging	interacts_with	disease	0.65
Immune Response	associated_with	pathway	0.60
APOPTOSIS	associated_with	gene	0.60
Apoptosis	associated_with	pathway	0.60
Akt	associated_with	pathway	0.60
EXERCISE	interacts_with	gene	0.60
FOXO1	associated_with	gene	0.60

Incoming (4)

Source	Relation	Type	Str
AGING	interacts_with	gene	0.60
SCFD1	interacts_with	gene	0.60
JAK2	interacts_with	gene	0.60
AKT	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KDM5D in their description or question text

No additional research found