gene

KCNN2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

7Outgoing

1Incoming

0Experiments

0Debates

Summary

Page for KCNN2 Gene

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🧬 Gene Info

Gene Symbol	KCNN2
Full Name	Potassium Calcium-Activated Channel Subfamily N Member 2
Chromosome	5q22.1
Protein Type	Channel
Function	encodes a neuronal small-conductance calcium-activated potassium channel with critical roles in synaptic plasticity, learning, and memory.
Subcellular Localization	dendritic compartments where they shape synaptic integration and plasticity. [@bond2004]
UniProt ID	Q9H5Y2
NCBI Gene ID	3777
Ensembl ID	ENSG00000162610
OMIM	609922
GeneCards	KCNN2
Human Protein Atlas	KCNN2
Associated Diseases	neurodegeneration
KG Connections	8 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNN2 — AlphaFold Q9H5Y2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNN2 Gene

gene · 874 words

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Pathway Diagram

graph TD
    KCNN2["KCNN2"]
    Schizophrenia{"Schizophrenia"}
    KCNN2 -->|"therapeutic target"| Schizophrenia
    Als{"Als"}
    KCNN2 -->|"therapeutic target"| Als
    Autism{"Autism"}
    KCNN2 -->|"therapeutic target"| Autism
    Depression{"Depression"}
    KCNN2 -->|"therapeutic target"| Depression
    Ms{"Ms"}
    KCNN2 -->|"therapeutic target"| Ms
    GRIA3["GRIA3"]
    KCNN2 -->|"associated with"| GRIA3
    KCNK2["KCNK2"]
    KCNN2 -->|"therapeutic target"| KCNK2
    neurodegeneration["neurodegeneration"]
    KCNN2 -->|"implicated in"| neurodegeneration
    KCNMB1["KCNMB1"]
    KCNMB1 -->|"therapeutic target"| KCNN2
    style KCNN2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (7)

Target	Relation	Type	Str
Schizophrenia	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Autism	therapeutic_target	disease	0.65
Depression	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
GRIA3	associated_with	gene	0.60
KCNK2	therapeutic_target	gene	0.60

Incoming (1)

Source	Relation	Type	Str
KCNMB1	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNN2 in their description or question text

No additional research found