gene

KCNMB1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNMB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

8Outgoing

0Incoming

0Experiments

0Debates

Summary

KCNMB1 Gene

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🧬 Gene Info

Gene Symbol	KCNMB1
Full Name	Potassium Calcium-Activated Channel Regulatory Subunit Beta 1
Chromosome	5q22.1
Function	KCNMB1 (Potassium Calcium-Activated Channel Regulatory Subunit Beta 1) encodes the beta-1 subunit of the large-conductance calcium-activated potassium (BK) channel, also known as MaxiK or Slo1.
Primary Expression	neurons where they regulate neuronal excitability, action potential duration, and neurotransmitter release
UniProt ID	KCNMB1
Ensembl ID	ENSG00000112984
GeneCards	KCNMB1
Human Protein Atlas	KCNMB1
Associated Diseases	neurodegeneration
KG Connections	8 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: KCNMB1 — AlphaFold KCNMB1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCNMB1 Gene

gene · 514 words

→

KCNMB1 (Potassium Calcium-Activated Channel Subfamily M Beta 1)

gene · 1921 words

→

Pathway Diagram

graph TD
    KCNMB1["KCNMB1"]
    Schizophrenia{"Schizophrenia"}
    KCNMB1 -->|"therapeutic target"| Schizophrenia
    Als{"Als"}
    KCNMB1 -->|"therapeutic target"| Als
    Autism{"Autism"}
    KCNMB1 -->|"therapeutic target"| Autism
    Depression{"Depression"}
    KCNMB1 -->|"therapeutic target"| Depression
    Ms{"Ms"}
    KCNMB1 -->|"therapeutic target"| Ms
    KCNN2["KCNN2"]
    KCNMB1 -->|"therapeutic target"| KCNN2
    GRIA3["GRIA3"]
    KCNMB1 -->|"therapeutic target"| GRIA3
    KCNK2["KCNK2"]
    KCNMB1 -->|"associated with"| KCNK2
    neurodegeneration["neurodegeneration"]
    KCNMB1 -->|"implicated in"| neurodegeneration
    style KCNMB1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (8)

Target	Relation	Type	Str
Schizophrenia	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Autism	therapeutic_target	disease	0.65
Depression	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
KCNN2	therapeutic_target	gene	0.60
GRIA3	therapeutic_target	gene	0.60
KCNK2	associated_with	gene	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNMB1 in their description or question text

No additional research found