gene

KCNK6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNK6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

12Outgoing

5Incoming

0Experiments

0Debates

Summary

Potassium two-pore domain channel gene KCNK6 (TASK-3)

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	KCNK6
Full Name	Potassium Two Pore Domain Channel Subfamily K Member 6
Aliases	TASK-3
Chromosome	19q13.2
Protein Type	Channel
Function	Key properties include
Primary Expression	the brain [@shieh2000]
UniProt ID	Q9Y5U5
NCBI Gene ID	9479
Ensembl ID	ENSG00000171303
GeneCards	KCNK6
Human Protein Atlas	KCNK6
Associated Diseases	neurodegeneration
KG Connections	17 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNK6 — AlphaFold Q9Y5U5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNK6 Gene

gene · 814 words

→

Pathway Diagram

graph TD
    KCNK6["KCNK6"]
    Hypertension{"Hypertension"}
    KCNK6 -->|"activates"| Hypertension
    Heart_Failure{"Heart Failure"}
    KCNK6 -->|"activates"| Heart_Failure
    Als{"Als"}
    KCNK6 -->|"activates"| Als
    Fibrosis{"Fibrosis"}
    KCNK6 -->|"inhibits"| Fibrosis
    KCNK6 -->|"inhibits"| Als
    ALS{"ALS"}
    KCNK6 -->|"activates"| ALS
    PAH["PAH"]
    KCNK6 -->|"regulates"| PAH
    KCNK2["KCNK2"]
    KCNK6 -->|"regulates"| KCNK2
    KCNK1["KCNK1"]
    KCNK6 -->|"associated with"| KCNK1
    KCNK6 -->|"associated with"| KCNK2
    KCNK6 -->|"regulates"| KCNK1
    KCNK3["KCNK3"]
    KCNK6 -->|"regulates"| KCNK3
    KCNK2 -->|"regulates"| KCNK6
    KCNK1 -->|"regulates"| KCNK6
    KCNK3 -->|"regulates"| KCNK6
    PAH -->|"regulates"| KCNK6
    KCNK5["KCNK5"]
    KCNK5 -->|"associated with"| KCNK6
    AND["AND"]
    AND -->|"regulates"| KCNK6
    style KCNK6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (12)

Target	Relation	Type	Str
Fibrosis	inhibits	disease	0.65
Als	inhibits	disease	0.65
ALS	activates	disease	0.65
Hypertension	activates	disease	0.65
Heart Failure	activates	disease	0.65
Als	activates	disease	0.65
KCNK1	associated_with	gene	0.60
KCNK2	associated_with	gene	0.60
PAH	regulates	gene	0.60
KCNK2	regulates	gene	0.60
KCNK1	regulates	gene	0.60
KCNK3	regulates	gene	0.60

Incoming (5)

Source	Relation	Type	Str
KCNK2	regulates	gene	0.60
KCNK1	regulates	gene	0.60
KCNK3	regulates	gene	0.60
PAH	regulates	gene	0.60
KCNK5	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNK6 in their description or question text

No additional research found