protein

KCNJ3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNJ3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

9Outgoing

3Incoming

0Experiments

0Debates

Summary

KCNJ3 is a protein involved in neurodegeneration research. Key relationships include: regulates, interacts with, associated with. Associated with Aging, Als, Autism. Connected to 13 entities in the SciDEX knowledge graph.

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🔬 Protein Info

Gene Symbol	KCNJ3
Protein Type	Protein
Function	The activation mechanism involves
Molecular Weight	57 kDa
Amino Acids	497 aa
UniProt ID	Search UniProt
GeneCards	KCNJ3
Human Protein Atlas	KCNJ3
Associated Diseases	Cancer, Ms
KG Connections	12 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: KCNJ3 — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    KCNJ3["KCNJ3"]
    Ms{"Ms"}
    KCNJ3 -->|"associated with"| Ms
    Cancer{"Cancer"}
    KCNJ3 -->|"associated with"| Cancer
    Als{"Als"}
    KCNJ3 -->|"interacts with"| Als
    Aging{"Aging"}
    KCNJ3 -->|"interacts with"| Aging
    KCNJ3 -->|"interacts with"| Ms
    Autism{"Autism"}
    KCNJ3 -->|"interacts with"| Autism
    KCNK2["KCNK2"]
    KCNJ3 -->|"regulates"| KCNK2
    KCNS1["KCNS1"]
    KCNJ3 -->|"regulates"| KCNS1
    GRIK1["GRIK1"]
    KCNJ3 -->|"associated with"| GRIK1
    neurodegeneration["neurodegeneration"]
    KCNJ3 -->|"implicated in"| neurodegeneration
    KCNJ6["KCNJ6"]
    KCNJ6 -->|"regulates"| KCNJ3
    KCNJ5["KCNJ5"]
    KCNJ5 -->|"regulates"| KCNJ3
    CANCER["CANCER"]
    CANCER -->|"associated with"| KCNJ3
    style KCNJ3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (9)

Target	Relation	Type	Str
Ms	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
Als	interacts_with	disease	0.65
Aging	interacts_with	disease	0.65
Ms	interacts_with	disease	0.65
Autism	interacts_with	disease	0.65
KCNK2	regulates	gene	0.60
KCNS1	regulates	gene	0.60
GRIK1	associated_with	gene	0.60

Incoming (3)

Source	Relation	Type	Str
CANCER	associated_with	gene	0.60
KCNJ6	regulates	gene	0.60
KCNJ5	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNJ3 in their description or question text

No additional research found