concept

INSC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INSC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections

0Hypotheses

0Analyses

28Outgoing

3Incoming

0Experiments

0Debates

No summary available yet.

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💡 Concept Info

Name	INSC
Key Genes/Proteins	AND, CREL, HMGCR, NEUROTOXICITY
Related Diseases	Multiple Sclerosis
Related Pathways	Cholesterol

Pathway Diagram

graph TD
    INSC["INSC"]
    INSC -->|"regulates"| Asymmetric_Stem_Cell_Division["Asymmetric Stem Cell Division"]
    INSC -->|"regulates"| Cell_Fate_Decision["Cell Fate Decision"]
    INSC -->|"involved_in"| Stem_Cell_Differentiation["Stem Cell Differentiation"]
    INSC -->|"involved_in"| Embryonic_Stem_Cell_Differenti["Embryonic Stem Cell Differentiation"]
    INSC -->|"expressed in"| Embryonic_Stem_Cell["Embryonic Stem Cell"]
    INSC -->|"involved_in"| Symmetric_Stem_Cell_Division["Symmetric Stem Cell Division"]
    INSC -->|"involved_in"| Mesendoderm_Development["Mesendoderm Development"]
    REL["REL"] -->|"regulates"| INSC
    CREL["CREL"] -->|"regulates"| INSC
    RNA["RNA"] -->|"inhibits"| INSC

Outgoing (28)

Target	Relation	Type	Str
Stem Cell Differentiation	involved_in	process	0.90
Cell Fate Decision	regulates	process	0.90
Asymmetric Stem Cell Division	regulates	process	0.90
Embryonic Stem Cell Differentiation	involved_in	process	0.90
Asymmetric Stem Cell Division	involved_in	process	0.85
Embryonic Stem Cell	expressed_in	cell_type	0.85
Symmetric Stem Cell Division	involved_in	process	0.85
Mesendoderm Development	involved_in	process	0.80
Multiple Sclerosis	activates	disease	0.65
Senescence	activates	disease	0.65
Stem Cell	activates	cell_type	0.60
Fibroblast	activates	cell_type	0.60
Neuron	activates	cell_type	0.60
Cholesterol	activates	pathway	0.60
HMGCR	activates	gene	0.60
RNA	regulates	gene	0.60
REL	regulates	gene	0.60
AND	expressed_in	gene	0.60
RNA	inhibits	gene	0.60
Neural Progenitor	activates	cell_type	0.60
stem cells	expressed_in	cell_type	0.60
Stem Cell	regulates	cell_type	0.60
AND	activates	gene	0.60
NEUROTOXICITY	activates	gene	0.60
Progenitor Cell	expressed_in	cell_type	0.55
Fibroblast	expressed_in	cell_type	0.55
Neuron	expressed_in	cell_type	0.55
Stem Cell	expressed_in	cell_type	0.55

Incoming (3)

Source	Relation	Type	Str
REL	regulates	gene	0.95
CREL	regulates	gene	0.95
RNA	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning INSC in their description or question text

No additional research found