concept

HOPX

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HOPX: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections

0Hypotheses

0Analyses

13Outgoing

7Incoming

0Experiments

0Debates

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💡 Concept Info

Name	HOPX
Key Genes/Proteins	AND, ANXA1, App, GBM, GFAP, LIF
Related Diseases	Als, ALS, glioblastoma

Pathway Diagram

graph TD
    HOPX["HOPX"]
    HOPX -.biomarker for.-> Mesoderm_Development["Mesoderm Development"]
    HOPX -->|"causes"| ALS["ALS"]
    HOPX -->|"expressed in"| Als["Als"]
    HOPX -->|"expressed in"| AND["AND"]
    HOPX -->|"expressed in"| Raf["Raf"]
    HOPX -->|"expressed in"| App["App"]
    HOPX -->|"activates"| Radial_Glia["Radial Glia"]
    HOPX -->|"activates"| Pericyte["Pericyte"]
    AND -->|"expressed in"| HOPX
    GFAP["GFAP"] -->|"expressed in"| HOPX
    LIFR["LIFR"] -->|"expressed in"| HOPX
    STAT3["STAT3"] -->|"activates"| HOPX
    LIF["LIF"] -->|"expressed in"| HOPX

Outgoing (13)

Target	Relation	Type	Str
Mesoderm Development	biomarker_for	process	0.80
Als	expressed_in	disease	0.65
ALS	causes	disease	0.65
App	expressed_in	protein	0.60
Radial Glia	activates	cell_type	0.60
Pericyte	activates	cell_type	0.60
Stem Cell	activates	cell_type	0.60
glioblastoma	causes	disease	0.60
AND	expressed_in	gene	0.60
Raf	expressed_in	protein	0.60
Stat3	activates	protein	0.60
Stem Cell	expressed_in	cell_type	0.55
Cortex	expressed_in	brain_region	0.55

Incoming (7)

Source	Relation	Type	Str
GFAP	expressed_in	gene	0.60
LIFR	expressed_in	gene	0.60
STAT3	activates	gene	0.60
LIF	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
ANXA1	causes	gene	0.60
GBM	causes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning HOPX in their description or question text

No additional research found