Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GPR56: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GPR56 |
| Pathways | Tgf-Β, Mtor |
| GeneCards | GPR56 |
| Human Protein Atlas | GPR56 |
| Associated Diseases | Als, Tumor |
| Interactions | AND, CX3CR1, DNA, GAL, MTOR, TCR |
| KG Connections | 21 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
graph TD
GPR56["GPR56"] -->|"associated"| Als["Als"]
style Als fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
GPR56["GPR56"] -->|"activates"| Carcinoma["Carcinoma"]
style Carcinoma fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
GPR56["GPR56"] -->|"associated"| Tumor["Tumor"]
style Tumor fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
GPR56["GPR56"] -.->|"inhibits"| AND["AND"]
style AND fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
GPR56["GPR56"] -.->|"inhibits"| TGFBR1["TGFBR1"]
style TGFBR1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
GPR56["GPR56"] -->|"activates"| Tgf__["Tgf-Beta"]
style Tgf__ fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
GPR56["GPR56"] -->|"activates"| TGM2["TGM2"]
style TGM2 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
SLC39A8["SLC39A8"] -->|"regulates"| GPR56["GPR56"]
style SLC39A8 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
GAL["GAL"] -.->|"inhibits"| GPR56["GPR56"]
style GAL fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
MTOR["MTOR"] -->|"activates"| GPR56["GPR56"]
style MTOR fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
style GPR56 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Carcinoma | activates | disease | 0.65 |
| Tumor | associated_with | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| AND | inhibits | gene | 0.60 |
| TGFBR1 | inhibits | gene | 0.60 |
| T cells | expressed_in | cell_type | 0.60 |
| Tgf-Β | activates | pathway | 0.60 |
| TCR | expressed_in | gene | 0.60 |
| TCR | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| MTOR | activates | gene | 0.60 |
| TGM2 | activates | gene | 0.60 |
| Mtor | activates | pathway | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GPR56 in their description or question text
No additional research found