concept

GLUTATHIONE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLUTATHIONE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

25Connections

0Hypotheses

0Analyses

15Outgoing

10Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GLUTATHIONE
Related Diseases	GLUTATHIONYLATION

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Glutathione Metabolism Pathway

mechanism · 3056 words

→

Pathway Diagram

graph TD
    GLUTATHIONE["GLUTATHIONE"]
    GLUTATHIONE -->|"promotes"| Tumor_Progression["Tumor Progression"]
    GLUTATHIONE -->|"activates"| MTOR["MTOR"]
    GLUTATHIONE -.protects against.-> Ferroptosis["Ferroptosis"]
    GLUTATHIONE -->|"binds"| SCARB2["SCARB2"]
    GLUTATHIONE -->|"activates"| GPX4["GPX4"]
    GLUTATHIONE -->|"inhibits"| Cuproptosis["Cuproptosis"]
    GCLC["GCLC"] -->|"involved_in"| GLUTATHIONE
    IDH2["IDH2"] -->|"upregulates"| GLUTATHIONE
    Cus_Md_Cs["Cus-Md@Cs"] -->|"downregulates"| GLUTATHIONE
    Adipocytes["Adipocytes"] -->|"expressed in"| GLUTATHIONE
    SBFI26["SBFI26"] -->|"downregulates"| GLUTATHIONE
    High_Fat_Diet["High-Fat Diet"] -->|"upregulates"| GLUTATHIONE
    cystine["cystine"] -->|"contributes to"| GLUTATHIONE

Outgoing (15)

Target	Relation	Type	Str
Tumor Microenvironment	associated_with	cell_type	0.95
Tumor Progression	promotes	process	0.95
MTOR	activates	protein	0.95
Ferroptosis	modulates	process	0.90
Ferroptosis	protects_against	process	0.90
SCARB2	binds	protein	0.90
Breast Cancer Progression	associated_with	process	0.90
Ferroptosis	inhibits	process	0.85
ferroptosis	inhibits	phenotype	0.85
Oxidative Stress	inhibits	process	0.80
Cuproptosis	inhibits	process	0.80
GPX4	activates	protein	0.80
Stimuli-responsive nanoplatforms	associated_with	compound	0.75
GLUTATHIONYLATION	participates_in	phenotype	0.72
Parkinson's Disease	biomarker_for	disease	0.70

Incoming (10)

Source	Relation	Type	Str
GCLC	involved_in	gene	0.95
Adipocytes	expressed_in	cell_type	0.90
GCLC	regulates	gene	0.90
Cus-Md@Cs	downregulates	drug	0.90
IDH2	upregulates	entity	0.90
SBFI26	downregulates	drug	0.88
High-Fat Diet	upregulates	phenotype	0.85
GPX4	associated_with	protein	0.85
SBFI26	associated_with	drug	0.85
cystine	contributes_to	drug	0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GLUTATHIONE in their description or question text

No additional research found