Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLUCONEOGENIC GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GLUCONEOGENIC GENES |
| Key Genes/Proteins | AMPK, AND, FOXO1, GENES, NAD, PP2A |
| Related Diseases | Als, Diabetes |
| Related Pathways | Tgf-Β |
graph TD
GLUCONEOGENIC_GENES["GLUCONEOGENIC GENES"]
GLUCONEOGENIC_GENES -->|"activates"| Diabetes["Diabetes"]
GLUCONEOGENIC_GENES -->|"activates"| Als["Als"]
GLUCONEOGENIC_GENES -->|"activates"| PP2A["PP2A"]
GLUCONEOGENIC_GENES -->|"activates"| SMAD3["SMAD3"]
GLUCONEOGENIC_GENES -->|"activates"| AMPK["AMPK"]
GLUCONEOGENIC_GENES -->|"activates"| FOXO1["FOXO1"]
SIRT1["SIRT1"] -->|"activates"| GLUCONEOGENIC_GENES
AND["AND"] -->|"activates"| GLUCONEOGENIC_GENES| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GLUCONEOGENIC GENES | data_in | dataset_row | 0.00 |
| Diabetes | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| Diabetes | regulates | disease | 0.65 |
| Als | regulates | disease | 0.65 |
| NAD | regulates | gene | 0.60 |
| SIRT1 | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| FOXO1 | activates | gene | 0.60 |
| PP2A | activates | gene | 0.60 |
| SMAD3 | activates | gene | 0.60 |
| Tgf-Β | activates | pathway | 0.60 |
| GENES | regulates | gene | 0.60 |
| AMPK | activates | gene | 0.60 |
| FOXO1 | regulates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GLUCONEOGENIC GENES | data_in | dataset_row | 0.00 |
| SIRT1 | activates | protein | 0.90 |
| AND | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GLUCONEOGENIC GENES in their description or question text
No additional research found