Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GFM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GFM1 |
| Key Genes/Proteins | HK2, HSP90, OPTN, PINK1, RNA, TOMM20 |
| Related Diseases | Alzheimer's disease, Huntington's disease, neurodegeneration, Parkinson's disease |
graph TD
GFM1[GFM1]
GFM1 -->|regulates| translation[translation]
GFM1 -->|regulates| mitochondrial_function[mitochondrial function]
GFM1 -->|expressed in| HK2[HK2]
GFM1 -->|phosphorylates| neurodegeneration[neurodegeneration]
GFM1 -.biomarker for.-> HSP90[HSP90]
GFM1 -.biomarker for.-> PINK1[PINK1]
GFM1 -.biomarker for.-> TOMM20[TOMM20]
GFM1 -->|interacts| OPTN[OPTN]
benchmark_ot_ad_answer_key_GFM[benchmark_ot_ad_answer_key:GFM1] -->|data_in| GFM1| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GFM1 | data_in | dataset_row | 0.00 |
| mitochondrial function | regulates | process | 0.70 |
| Parkinson's disease | associated_with | disease | 0.70 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| Huntington's disease | associated_with | disease | 0.70 |
| translation | regulates | process | 0.70 |
| OPTN | interacts_with | gene | 0.60 |
| HK2 | expressed_in | gene | 0.60 |
| neurodegeneration | implicated_in | disease | 0.60 |
| neurodegeneration | phosphorylates | disease | 0.60 |
| HSP90 | biomarker_for | gene | 0.60 |
| PINK1 | biomarker_for | gene | 0.60 |
| TOMM20 | biomarker_for | gene | 0.60 |
| mitochondrial function | participates_in | pathway | 0.60 |
| RNA | associated_with | gene | 0.60 |
| T cells | expressed_in | cell_type | 0.60 |
| Parkinson's disease | phosphorylates | disease | 0.60 |
| Huntington's disease | phosphorylates | disease | 0.60 |
| Alzheimer's disease | phosphorylates | disease | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:GFM1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GFM1 in their description or question text
No additional research found