gene

FZD9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FZD9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

10Outgoing

6Incoming

0Experiments

0Debates

Summary

Gene encoding the Frizzled-9 receptor, a key component of Wnt signaling pathways involved in neurodevelopment, synaptic plasticity, and neurodegenerative disease.

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🧬 Gene Info

Gene Symbol	FZD9
Full Name	Frizzled Class Receptor 9
Chromosome	7q11.23.
Protein Type	Receptor
Function	encodes a member of the Frizzled family of receptors, which are essential components of the Wnt signaling pathway.
Amino Acids	585 aa
Exons	8
Pathways	Wnt signaling, Wnt, Wnt pathway
UniProt ID	O00107
NCBI Gene ID	2865
GeneCards	FZD9
Human Protein Atlas	FZD9
Associated Diseases	neurodegeneration
KG Connections	16 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FZD9 — AlphaFold O00107 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

FZD9 Gene

gene · 1009 words

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FZD9 Protein

protein · 1456 words

→

Pathway Diagram

graph TD
    FZD9["FZD9"]
    Als{"Als"}
    FZD9 -->|"regulates"| Als
    Ms{"Ms"}
    FZD9 -->|"regulates"| Ms
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    FZD9 -->|"regulates"| Amyotrophic_Lateral_Sclerosis
    FZD2["FZD2"]
    FZD9 -->|"regulates"| FZD2
    GRB2["GRB2"]
    FZD9 -->|"regulates"| GRB2
    AMYOTROPHIC_LATERAL_SCLEROSIS["AMYOTROPHIC LATERAL SCLEROSIS"]
    FZD9 -->|"regulates"| AMYOTROPHIC_LATERAL_SCLEROSIS
    ALS["ALS"]
    FZD9 -->|"regulates"| ALS
    EIF2AK2["EIF2AK2"]
    FZD9 -->|"regulates"| EIF2AK2
    CREBBP["CREBBP"]
    FZD9 -->|"regulates"| CREBBP
    Wnt(["Wnt"])
    FZD9 -->|"regulates"| Wnt
    neurodegeneration["neurodegeneration"]
    FZD9 -->|"implicated in"| neurodegeneration
    PIK3CA["PIK3CA"]
    PIK3CA -->|"regulates"| FZD9
    CD44["CD44"]
    CD44 -->|"regulates"| FZD9
    MOTOR_NEURONS["MOTOR NEURONS"]
    MOTOR_NEURONS -->|"regulates"| FZD9
    SRC["SRC"]
    SRC -->|"regulates"| FZD9
    EEF2["EEF2"]
    EEF2 -->|"regulates"| FZD9
    SOD1["SOD1"]
    SOD1 -->|"regulates"| FZD9
    style FZD9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (10)

Target	Relation	Type	Str
Als	regulates	disease	0.65
Ms	regulates	disease	0.65
Amyotrophic Lateral Sclerosis	regulates	disease	0.65
AMYOTROPHIC LATERAL SCLEROSIS	regulates	gene	0.60
ALS	regulates	gene	0.60
FZD2	regulates	gene	0.60
GRB2	regulates	gene	0.60
EIF2AK2	regulates	gene	0.60
CREBBP	regulates	gene	0.60
Wnt	regulates	pathway	0.60

Incoming (6)

Source	Relation	Type	Str
PIK3CA	regulates	gene	0.60
CD44	regulates	gene	0.60
SRC	regulates	gene	0.60
EEF2	regulates	gene	0.60
SOD1	regulates	gene	0.60
MOTOR NEURONS	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FZD9 in their description or question text

No additional research found