concept

FPN1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FPN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

11Outgoing

4Incoming

0Experiments

0Debates

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💡 Concept Info

Name	FPN1
Key Genes/Proteins	ACSL4, FTH1, FTL, GPX4, SLC7A11
Related Pathways	ferroptosis, oxidative stress response

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

FPN1 (Ferroportin)

entity · 790 words

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Pathway Diagram

graph TD
    FPN1[FPN1]
    FPN1 -->|expressed in| FTH1[FTH1]
    FPN1 -->|expressed in| FTL[FTL]
    FPN1 -->|expressed in| GPX4[GPX4]
    FPN1 -->|expressed in| SLC7A11[SLC7A11]
    FPN1 -->|participates in| ferroptosis[ferroptosis]
    FPN1 -->|participates in| oxidative_stress_response[oxidative stress response]
    Chronic_cerebral_hypoperfusion[Chronic cerebral hypoperfusion] -->|downregulates| FPN1
    ACSL4[ACSL4] -->|expressed in| FPN1
    benchmark_ot_ad_answer_key_FPN[benchmark_ot_ad_answer_key:FPN1] -->|data_in| FPN1

Outgoing (11)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:FPN1	data_in	dataset_row	0.00
FTH1	expressed_in	gene	0.60
FTL	expressed_in	gene	0.60
GPX4	expressed_in	gene	0.60
SLC7A11	expressed_in	gene	0.60
ferroptosis	participates_in	pathway	0.60
FTH1	inhibits	gene	0.60
FTL	inhibits	gene	0.60
GPX4	inhibits	gene	0.60
SLC7A11	inhibits	gene	0.60
oxidative stress response	participates_in	pathway	0.60

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:FPN1	data_in	dataset_row	0.00
Chronic cerebral hypoperfusion	downregulates	process	0.85
ACSL4	expressed_in	gene	0.60
ACSL4	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FPN1 in their description or question text

No additional research found