entity

DOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections
3Hypotheses
1Analyses
2Outgoing
3Incoming
1Experiments
1Debates

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Wiki Pages (6)

Knowledge base pages for this entity

ADORA3 Gene

gene · 1758 words

ADORA2A Gene

gene · 1396 words

ADORA1 Gene

gene · 1272 words

Delta Opioid Receptor (DOR) Neurons

cell · 1201 words

ADORA2B Protein

protein · 1104 words

Outgoing (2)

TargetRelationTypeStr
C1Qbindsprotein0.80
ALZHEIMER'S_DISEASEassociated_withdisease0.80

Incoming (3)

SourceRelationTypeStr
C1Qbindsgene0.90
UFP_512activatesgene0.80
UFP-512activatesgene0.70

Targeting Hypotheses (3)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Parthenolide reduces tonic ADORA2A signaling by lowering inf 0.640 neuropharmacology How does parthenolide specifically modul
Parthenolide perturbs adenosine transport or metabolism upst 0.530 neuropharmacology How does parthenolide specifically modul
Parthenolide changes ADORA2A coupling efficiency through mem 0.489 neuropharmacology How does parthenolide specifically modul

Mentioning Analyses (1)

Scientific analyses that reference this entity

How does parthenolide specifically modulate ADORA2A signaling to produce antidep

neuropharmacology | 2026-04-25 | 3 hypotheses Top: 0.640

Experiments (1)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
Longitudinal dietary change analysis and ADRD risk over 10 years clinical Alzheimer's disease and relate 0.930 0.00 human patients proposed N/A

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

How does parthenolide specifically modulate ADORA2A signaling to produce antidep

active · Rounds: 4 · Score: 0.66 · 2026-04-25

Related Research

Hypotheses and analyses mentioning DOR in their description or question text

No additional research found