protein

CDNFPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDNFPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Debates

Summary

Cerebral Dopamine Neurotrophic Factor is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	CDNFPROTEIN
Full Name	Cerebral Dopamine Neurotrophic Factor (CDNF)
Protein Family	CDNF, ARMET/MANF family-like proteins
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	</td><td>Secreted, endoplasmic reticulum</td></tr>
Molecular Weight	~18 kDa (160 amino acids)
Amino Acids	160 aa
UniProt ID	Q96GS4
GeneCards	CDNFPROTEIN
Human Protein Atlas	CDNFPROTEIN
N-terminal signal peptide	Directs secretion via the classical secretory pathway
Armadillo-repeat domain	Forms a superhelical structure involved in protein-protein interactions
C-terminal domain	Contains a conserved MANF-like fold with a metal-binding motif
disulfide bonds	Three conserved cysteine residues form stabilizing disulfide bridges
Associated Diseases	ALS, Alzheimer, Parkinson
Known Drugs/Compounds	levodopa
Interactions	ALZHEIMER, ALZHEIMER'S DISEASE, PARKINSON, PARKINSON'S DISEASE
KG Connections	32 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CDNFPROTEIN — AlphaFold Q96GS4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Cerebral Dopamine Neurotrophic Factor

protein · 1504 words

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Pathway Diagram

graph TD
    CDNFPROTEIN["CDNFPROTEIN"]
    neurodegeneration["neurodegeneration"]
    CDNFPROTEIN -->|"implicated_in"| neurodegeneration
    style CDNFPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CDNFPROTEIN in their description or question text

No additional research found