gene

BICD2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BICD2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

8Outgoing

4Incoming

0Experiments

0Debates

Summary

BICD2 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in, expressed in. Associated with Als, Cancer. Connected to 14 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	BICD2
Chromosome	9q22.31
Function	BICD2 (BICD cargo adaptor 2) is a member of the BICD family of proteins that function as adaptors linking dynein-dynactin motor complexes to cargo vesicles.
UniProt ID	BICD2
Ensembl ID	ENSG00000176177
GeneCards	BICD2
Human Protein Atlas	BICD2
Associated Diseases	Als, Cancer
KG Connections	12 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

BICD2 Gene

gene · 657 words

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Pathway Diagram

graph TD
    BICD2["BICD2"]
    TREM2["TREM2"]
    BICD2 -->|"associated with"| TREM2
    microglia["microglia"]
    BICD2 -->|"expressed in"| microglia
    neurodegeneration["neurodegeneration"]
    BICD2 -->|"associated with"| neurodegeneration
    Als{"Als"}
    BICD2 -->|"associated with"| Als
    Cancer{"Cancer"}
    BICD2 -->|"associated with"| Cancer
    MITF["MITF"]
    BICD2 -->|"associated with"| MITF
    CANCER["CANCER"]
    BICD2 -->|"associated with"| CANCER
    HSPA1A["HSPA1A"]
    BICD2 -->|"associated with"| HSPA1A
    BRCA2["BRCA2"]
    BICD2 -->|"associated with"| BRCA2
    BICD2 -->|"implicated in"| neurodegeneration
    KDM4A["KDM4A"]
    KDM4A -->|"associated with"| BICD2
    FGFR3["FGFR3"]
    FGFR3 -->|"associated with"| BICD2
    TP53["TP53"]
    TP53 -->|"associated with"| BICD2
    KRAS["KRAS"]
    KRAS -->|"associated with"| BICD2
    style BICD2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (8)

Target	Relation	Type	Str
TREM2	associated_with	gene	0.80
microglia	expressed_in	cell_type	0.80
Als	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
CANCER	associated_with	gene	0.60
HSPA1A	associated_with	gene	0.60
BRCA2	associated_with	gene	0.60
MITF	associated_with	gene	0.60

Incoming (4)

Source	Relation	Type	Str
KDM4A	associated_with	gene	0.60
FGFR3	associated_with	gene	0.60
TP53	associated_with	gene	0.60
KRAS	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BICD2 in their description or question text

No additional research found