gene

arx

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about arx: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections

0Hypotheses

0Analyses

7Outgoing

2Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	ARX
Full Name	Aristaless-Related Homeobox
Chromosome	Xp21.3
Protein Type	Transcription Factor
Function	ARX plays critical roles in development and function
Amino Acids	60 aa
Gene Type	Protein coding
UniProt ID	Q9NUJ1
NCBI Gene ID	566
Ensembl ID	ENSG00000031081
OMIM	300382
GeneCards	ARX
Human Protein Atlas	ARX
Associated Diseases	Als, neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: arx — AlphaFold Q9NUJ1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

ARX Gene

gene · 661 words

→

karxt-nct07011745

clinical_trial · 2975 words

→

Pathway Diagram

flowchart TD
    N0["ARX"]
    N1["Als"]
    N0 -->|"associated with"| N1
    N2["Ms"]
    N0 -->|"regulates"| N2
    N3["GENES"]
    N0 -->|"interacts with"| N3
    N4["PER"]
    N0 -->|"associated with"| N4
    N5["Differentiation"]
    N0 -->|"associated with"| N5
    N6["Synaptic Plasticity"]
    N0 -->|"associated with"| N6
    N7["FMR1"]
    N7 -->|"interacts with"| N0
    N8["neurodegeneration"]
    N0 -->|"implicated in"| N8

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 pathway
    class N6 pathway
    class N7 gene

Outgoing (7)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ARX	data_in	dataset_row	0.00
Als	associated_with	disease	0.65
Ms	regulates	disease	0.65
GENES	interacts_with	gene	0.60
PER	associated_with	gene	0.60
Differentiation	associated_with	pathway	0.60
Synaptic Plasticity	associated_with	pathway	0.60

Incoming (2)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ARX	data_in	dataset_row	0.00
FMR1	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning arx in their description or question text

No additional research found