gene

ap2m1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ap2m1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections

0Hypotheses

0Analyses

6Outgoing

5Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	AP2M1
Full Name	Adaptor Related Protein Complex 2 Subunit Mu 1
Chromosome	3p24.3
Function	is a hydrophobic residue).
Molecular Weight	50 kDa
Amino Acids	435 aa
Exons	16
UniProt ID	Q96CW1
NCBI Gene ID	1173
Ensembl ID	ENSG00000161298
OMIM	601024
GeneCards	AP2M1
Human Protein Atlas	AP2M1
Associated Diseases	Alzheimer's Disease
Interactions	AND, AP2A1, AUTOPHAGY, LC3
KG Connections	11 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ap2m1 — AlphaFold Q96CW1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

AP2M1 Gene

gene · 3193 words

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Pathway Diagram

flowchart TD
    N0["AP2M1"]
    N1["AUTOPHAGY"]
    N0 -->|"activates"| N1
    N2["LC3"]
    N0 -->|"activates"| N2
    N3["Autophagy"]
    N0 -->|"activates"| N3
    N4["Endocytosis"]
    N0 -->|"activates"| N4
    N5["AP2A1"]
    N5 -->|"activates"| N0
    N6["AND"]
    N6 -->|"activates"| N0
    N2 -->|"activates"| N0
    N7["neurodegeneration"]
    N0 -->|"implicated in"| N7

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 pathway
    class N4 pathway
    class N5 gene
    class N6 gene

Outgoing (6)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:AP2M1	data_in	dataset_row	0.00
ds-83b31ef18d49	provides_data_for	dataset	1.00
LC3	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
Autophagy	activates	pathway	0.60
Endocytosis	activates	pathway	0.60

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:AP2M1	data_in	dataset_row	0.00
ds-83b31ef18d49	data_in	dataset	1.00
AP2A1	activates	gene	0.60
AND	activates	gene	0.60
LC3	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ap2m1 in their description or question text

No additional research found