gene

ant2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ant2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections

0Hypotheses

0Analyses

19Outgoing

2Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ANT2
Full Name	Adenine Nucleotide Translocator 2 (ANT2)
Aliases	SLC25A5
Chromosome	Xq26.3
Function	is a mitochondrial inner membrane protein that catalyzes the exchange of ADP and ATP across the inner mitochondrial membrane.
Primary Expression	most tissues, including the brain
Molecular Weight	33 kDa
Amino Acids	322 aa
UniProt ID	P02724
NCBI Gene ID	291
Ensembl ID	ENSG00000148218
OMIM	300120
GeneCards	ANT2
Human Protein Atlas	ANT2
Associated Diseases	Alzheimer's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ant2 — AlphaFold P02724 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ANT2 (Adenine Nucleotide Translocator 2)

gene · 1995 words

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Pathway Diagram

graph TD
    ANT2["ANT2"]
    ANT2 -->|"implicated in"| Tumorigenesis["Tumorigenesis"]
    ANT2 -->|"implicated in"| Drug_Resistance["Drug Resistance"]
    ANT2 -->|"regulates"| Glycolytic_ATP_Import["Glycolytic ATP Import"]
    ANT2 -->|"participates in"| Blood_Cell_Development["Blood Cell Development"]
    ANT2 -->|"participates in"| Gastrointestinal_Motility["Gastrointestinal Motility"]
    ANT2 -->|"participates in"| Airway_Hydration["Airway Hydration"]
    ANT2 -->|"participates in"| Myocardial_Development["Myocardial Development"]
    ANT2 -->|"activates"| Hepatitis["Hepatitis"]
    TFEB["TFEB"] -->|"activates"| ANT2

Outgoing (19)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ANT2	data_in	dataset_row	0.00
Tumorigenesis	implicated_in	biological_process	0.80
Glycolytic ATP Import	regulates	biological_process	0.80
Gastrointestinal Motility	participates_in	biological_process	0.70
Airway Hydration	participates_in	biological_process	0.70
Nonalcoholic Fatty Liver Disease	associated_with	disease	0.70
Myocardial Development	participates_in	biological_process	0.70
Blood Cell Development	participates_in	biological_process	0.70
Obesity	associated_with	disease	0.70
Chronic Kidney Disease	associated_with	disease	0.70
Hepatitis	activates	disease	0.65
Ms	activates	disease	0.65
Inflammation	activates	disease	0.65
INFLAMMATION	activates	gene	0.60
Mtor	activates	pathway	0.60
HIF	activates	gene	0.60
GENES	activates	gene	0.60
MTOR	activates	gene	0.60
TFEB	activates	gene	0.60

Incoming (2)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ANT2	data_in	dataset_row	0.00
TFEB	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ant2 in their description or question text

No additional research found