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PGC-1α Protein

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wiki page Created: 2026-04-02T20:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-proteins-pgc-1-alpha

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📊 Evidence Profile

Evidence Balance

+0%

Certainty

100%

Debates

0

Incoming

26

Outgoing

39

0 supporting 0 contradicting 0 neutral

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Linked Artifacts (65)

mentions🧫TUG C-terminal product nuclear localization and PPARγ bindin70%

mentions🧫Activity-dependent PGC-1α transcriptional program analysis70%

mentions🧫PGC-1α knockout analysis of PV+ interneuron maturation70%

mentions🧫Differential GWAS of schizophrenia vs PTSD70%

mentions🧫PGC-1α expression analysis during PV+ interneuron developmen70%

mentions🧫Cytochrome Therapeutics70%

mentions🧫Activity-dependent regulation of PGC-1α in PV+ interneurons70%

mentions🧫GWAS meta-analysis of major depressive disorder across three70%

mentions🧫PV+ interneuron subtype diversification analysis70%

mentions🧫Sirtuin Pathway Dysfunction Validation in Parkinson's D70%

mentions🧫Synaptic Mitochondrial Resilience Enhancement for Parkinson&70%

mentions🧫TUG C-terminal fragment nuclear interactions70%

mentions🧫PGC-1α knockout effects on PV+ interneuron maturation70%

mentions🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration65%

mentions🧪Arginine Methylation Enhancement Therapy65%

related🧫PGC-1α knockout analysis of PV+ interneuron maturation63%

related🧫Differential GWAS of schizophrenia vs PTSD63%

related🧫Cytochrome Therapeutics63%

related🧫Sirtuin Pathway Dysfunction Validation in Parkinson's D63%

related🧫GWAS meta-analysis of major depressive disorder across three63%

related🧫PV+ interneuron subtype diversification analysis63%

related🧫Activity-dependent regulation of PGC-1α in PV+ interneurons63%

related🧫Synaptic Mitochondrial Resilience Enhancement for Parkinson&63%

related🧫PGC-1α knockout effects on PV+ interneuron maturation63%

related🧫TUG C-terminal fragment nuclear interactions63%

related🧫PGC-1α expression analysis during PV+ interneuron developmen63%

related🧫TUG C-terminal product nuclear localization and PPARγ bindin63%

related🧫Activity-dependent PGC-1α transcriptional program analysis63%

see_also📖lmx1b60%

see_also📖Neurofilament Medium Chain (NfM) - Biomarker60%

see_also📖ER Stress and Unfolded Protein Response in Corticobasal Dege60%

see_also📖HNRNPA1 Gene60%

see_also📖APP Gene Dosage Reduction Therapy for Down Syndrome60%

see_also📖Parkinson Basal Ganglia Circuit60%

see_also📖NURR1 Gene60%

see_also📖park760%

related🧪Arginine Methylation Enhancement Therapy58%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬What are the mechanisms underlying tdp-43 phase separation t50%

mentions🧪Nutrient-Sensing Epigenetic Circuit Reactivation50%

mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬Epigenetic reprogramming in aging neurons50%

related🔬How to break the GBA-alpha-synuclein bidirectional loop for 50%

related🔬What are the mechanisms underlying protein aggregation cross50%

mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

mentions🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m50%

related🔬RNA binding protein dysregulation across ALS FTD and AD50%

related🔬Epigenetic reprogramming in aging neurons50%

mentions🧪TFAM overexpression creates mitochondrial donor-recipient gr50%

mentions🔬What are the mechanisms underlying protein aggregation cross40%

mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%

related🧪Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration40%

mentions🧪Digital Twin-Guided Metabolic Reprogramming40%

related🧪Heat Shock Protein 70 Disaggregase Amplification40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

mentions🔬How to break the GBA-alpha-synuclein bidirectional loop for 40%

related🧪Serine/Arginine-Rich Protein Kinase Modulation40%

mentions🔬What are the mechanisms underlying rna binding protein dysre40%

related🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m40%

mentions🧪Perforant Path Presynaptic Terminal Protection Strategy40%

mentions🔬Epigenetic reprogramming in aging neurons35%

related🔬What are the mechanisms underlying tdp-43 phase separation t30%

💬 Discussion