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GWAS meta-analysis of major depressive disorder across three cohorts

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experiment Created: 2026-04-06T19:30:40 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-5f1ec586-f80a-4c02-9641-6

🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

experiment-exp-5f1ec586-f80a-4→paper-29728651

📊 Evidence Profile

Evidence Balance

+0%

Certainty

65%

Debates

0

Incoming

13

Outgoing

13

0 supporting 0 contradicting 0 neutral

View full evidence profile →

Linked Artifacts (26)

derives_from📄Common variants on 6q16.2, 12q24.31 and 16p13.3 are associat100%

mentions📖PGC-1α and Mitochondrial Biogenesis Therapies for Parkinson&70%

mentions📖GWAS Findings Hub70%

mentions📖proteins-pgc-1a-protein70%

mentions📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis70%

mentions📖PGC-1 Alpha70%

mentions📖PGC-1α Mitochondrial Biogenesis Comparison — AD/PD/ALS/FTD/H70%

mentions📖PGC-1α (PPARGC1A) Targeted Therapies in Neurodegeneration70%

mentions📖PGC-1β Protein70%

mentions📖PGC-1α Protein70%

mentions📖PGC-1α (PPARGC1A)70%

mentions📖PGC-1α Activator Therapy for Neurodegeneration70%

related📖PGC-1α (PPARGC1A)63%

related📖PGC-1α and Mitochondrial Biogenesis Therapies for Parkinson&63%

related📖PGC-1 Alpha63%

related📖PGC-1α Protein63%

related📖PGC-1α (PPARGC1A) Targeted Therapies in Neurodegeneration63%

related📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis63%

related📖PGC-1β Protein63%

related📖proteins-pgc-1a-protein63%

related📖PGC-1α Activator Therapy for Neurodegeneration63%

related📖GWAS Findings Hub63%

related📖PGC-1α Mitochondrial Biogenesis Comparison — AD/PD/ALS/FTD/H63%

related📖Depression (Major Depressive Disorder)60%

mentions📖Depression (Major Depressive Disorder)60%

related📖Depression (Major Depressive Disorder)54%

💬 Discussion