gene 1,286 words KG: SMN2
Contents

SMN2 Gene

🧬 Gene Info
Gene SymbolSMN2
Full NameSurvival of Motor Neuron 2, Telomeric
Chromosome5q13.2.
FunctionThe SMN complex plays a critical role in pre-mRNA splicing by facilitating the biogenesis of U1, U2, U4, and U5 snRNPs[@pellizzoni2002].
Molecular Weight32 kDa
Amino Acids294 aa
UniProt IDQ16637
NCBI Gene ID6609
Ensembl IDENSG00000120247
OMIM601627
GeneCardsSMN2
Human Protein AtlasSMN2
Associated DiseasesAls
InteractionsMOTOR NEURONS, NEURON, Rb, SMN1
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

SMN2 expressed_in SMN1
SMN2 therapeutic_target Mrna Processing
SMN1 interacts_with SMN2
SMN associated_with SMN2
SMN2 interacts_with SMN1
SMN2 interacts_with Spinal Muscular Atrophy
SMN2 interacts_with Rb
AXON therapeutic_target SMN2
SMN2 therapeutic_target MOTOR NEURONS
SMN2 therapeutic_target NEURON

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