protein 1,322 words KG: XIAPPROTEIN
Contents

X-linked Inhibitor of Apoptosis Protein (XIAP)

🔬 Protein Info
Gene SymbolXIAP
Full NameX-Linked Inhibitor of Apoptosis
AliasesXIAPPROTEIN
ChromosomeXq25
FunctionXIAP (X-linked Inhibitor of Apoptosis) is the best-characterized member of the Inhibitor of Apoptosis (IAP) protein family.
Primary Expressionneuronal tissues where it protects against apoptosis induced by various stimuli including oxidative stress, mitochondrial dysfu
PathwaysNF-κB
UniProt ID[P98170](https://www.uniprot.org/uniprot/P98170)
Ensembl IDENSG00000101966
GeneCardsXIAP
Human Protein AtlasXIAP
Structural scaffoldDoes not directly inhibit caspases
TAB1 bindingMediates interaction with TAK1-binding protein 1
Associated DiseasesCancer, Ms
InteractionsACHE, AKT, ALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK
KG Connections211 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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