| Gene Symbol | USP14 |
| Aliases | USP14PROTEIN |
| Protein Type | Enzyme |
| Function | USP14 encodes a 494 amino acid cysteine protease belonging to the ubiquitin-specific protease (USP) family. |
| Amino Acids | 494 aa |
| Pathways | Er Stress, Autophagy, Immunotherapy |
| Ensembl ID | ENSG00000101557 |
| GeneCards | USP14 |
| Human Protein Atlas | USP14 |
| N-terminal UBL domain | Binds to proteasome 19S regulatory particle |
| Catalytic domain | Contains the DUB activity |
| Proteasome-interacting motif | Mediates association with the 19S cap |
| Associated Diseases | Als, Atherosclerosis, Cardiovascular, Neurodegenerative Diseases, Parkinson's Disease |
| Interactions | ATXN3, AUTOPHAGY, BRCC3, CANCER, CYLD, PINK1 |
| KG Connections | 48 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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