protein 748 words KG: UGCGPROTEIN
Contents

UGCG Protein (UDP-Glucose Ceramide Glucosyltransferase)

🔬 Protein Info
Gene SymbolUGCG
AliasesUDP-Glucose Ceramide Glucosyltransferase
FunctionThe UGCG gene encodes UDP-glucose ceramide glucosyltransferase (UGCG), also known as glucosylceramide synthase.
Primary Expressionglial cells including astrocytes and oligodendrocytes
Subcellular Localization** | Golgi apparatus |
Molecular Weight46 kDa
PathwaysApoptosis, Nf-Κb, Oxidative Stress, Wnt, apoptosis pathway
Ensembl IDENSG00000165269
GeneCardsUGCG
Human Protein AtlasUGCG
Associated DiseasesAls
InteractionsAPOPTOSIS, CD63, CD9, ERK, OXIDATIVE STRESS, RAB35
KG Connections27 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Sphingolipid Metabolism Reprogramming
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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