| Gene Symbol | TLR9 |
| Full Name | Toll-Like Receptor 9 |
| Aliases | TLR9PROTEIN |
| Chromosome | 3p21.3 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | microglia, astrocytes, and neurons, where it plays a critical role in innate immune responses to pathogen-a |
| Pathways | NF-κB, MAPK pathway |
| OMIM | 605203 |
| GeneCards | TLR9 |
| Human Protein Atlas | TLR9 |
| Leucine-rich repeat (LRR) domain | DNA binding |
| Transmembrane region | Endosomal localization |
| TIR domain | Intracellular signaling |
| DNA sensor | Recognizes CpG DNA motifs |
| Associated Diseases | ALS, Carcinoma, Cirrhosis, Cystic Fibrosis, Fibrosis, Hepatitis |
| Interactions | AIM2, AMPK, APOE, APOPTOSIS, CD68, Cytokine |
| KG Connections | 206 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!