| Gene Symbol | RTN4 |
| Full Name | Reticulon 4 |
| Aliases | Reticulon 4, Nogo |
| Chromosome | 22q11.21 |
| Function | encodes a family of reticulon proteins with three major isoforms: Nogo-A, Nogo-B, and Nogo-C[@schwab2010]. |
| Primary Expression | neurons and oligodendrocytes, where it acts through the Nogo-66 receptor (NgR) and its coreceptor |
| Molecular Weight | 200 kDa |
| Amino Acids | 66 aa |
| Pathways | Autophagy |
| UniProt ID | Q9NPD4 |
| NCBI Gene ID | 57142 |
| Ensembl ID | ENSG00000145113 |
| OMIM | 604569 |
| GeneCards | RTN4 |
| Human Protein Atlas | RTN4 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Interactions | BAI1, BECN1, MAP1LC3B |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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