protein 1,699 words KG: PTBP1PROTEIN
Contents

PTBP1 Protein — Polypyrimidine Tract Binding Protein 1

🔬 Protein Info
Gene SymbolPTBP1
Full NamePolypyrimidine Tract Binding Protein 1
AliasesPTBP1PROTEIN
Chromosome19p13.3.
Functionis a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of RNA-binding proteins.
Primary Expressionneural progenitor cells and declines as neurons differentiate
Molecular Weight57 kDa
Amino Acids531 aa
Exons15
PathwaysAutophagy, Epigenetic, Glycolysis, Innate Immunity, Stem Cell
Ensembl IDENSG00000064102
GeneCardsPTBP1
Human Protein AtlasPTBP1
Associated DiseasesAls
InteractionsATG, ATG10, ATG5, AUTOPHAGY, CALCOCO2, CANCER
KG Connections100 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (8)

Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

Key Papers (1)

Assessment of the Spatial Distribution of Moisture Content in Granular
Sensors (Basel, Switzerland) 2024

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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