| Gene Symbol | PIN1 |
| Full Name | Peptidyl-prolyl cis-trans Isomerase NIMA-Interacting 1 |
| Aliases | PIN1PROTEIN |
| Protein Type | Isomerase |
| Function | PIN1 is a unique peptidyl-prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of peptide bonds preceding phosphorylated serine or threonine residues. |
| Amino Acids | 163 aa |
| Pathways | MAPK, PI3K, Wnt, NF-κB |
| Ensembl ID | ENSG00000100429 |
| GeneCards | PIN1 |
| Human Protein Atlas | PIN1 |
| N-terminal WW domain | Recognizes phosphorylated serine/threonine-proline (pSer/Thr-Pro) motifs |
| C-terminal PPIase domain | Catalyzes prolyl isomerization |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease, Cancer, Dementia, Inflammation |
| Interactions | AD, AND, ANXA2, AΒ, CANCER, CYP46A1 |
| KG Connections | 178 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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