| Gene Symbol | OPRD1 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Plasma membrane, presynaptic vesicles</td></tr> |
| Amino Acids | 372 aa |
| Pathways | MAPK pathway, PI3K, MAPK |
| Ensembl ID | ENSG00000116381 |
| GeneCards | OPRD1 |
| Human Protein Atlas | OPRD1 |
| Extracellular N-terminus | Contains glycosylation sites and contributes to ligand binding |
| Intracellular C-terminus | Contains phosphorylation sites for receptor regulation |
| Third intracellular loop | Important for G protein coupling |
| Orthosteric binding site | Located within the transmembrane bundle |
| Allosteric binding sites | Additional sites for modulator binding |
| Crystal structures available | 8R0Y, 7RXC |
| Associated Diseases | Alzheimer's Disease, Anorexia, Heroin Dependence, Opioid Addiction |
| Interactions | OPRM1 |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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