| Gene Symbol | NMNAT2 |
| Full Name | NMN Adenylyltransferase 2 |
| Chromosome | 1p36.22 |
| Protein Type | Enzyme |
| Function | NMNAT2 is a cytosolic enzyme that catalyzes the conversion of NMN (nicotinamide mononucleotide) to NAD+ (nicotinamide adenine dinucleotide). |
| Molecular Weight | 46.2 kDa |
| Pathways | Complement, Immune Response, Mapk |
| UniProt ID | Q9H0M0 |
| NCBI Gene ID | 23257 |
| Ensembl ID | ENSG00000145425 |
| OMIM | 608401 |
| GeneCards | NMNAT2 |
| Human Protein Atlas | NMNAT2 |
| N-terminal Domain | Variable region involved in axonal targeting |
| Adenylyltransferase Domain | Central catalytic domain (~350 aa) that binds NMN and ATP |
| Associated Diseases | neurodegeneration |
| Interactions | AND, AXON, C4B, COMPLEMENT, MAPK, NEURODEGENERATIVE DISEASES |
| KG Connections | 22 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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