protein 740 words KG: LGALS1PROTEIN
Contents

LGALS1 Protein — Galectin-1

🔬 Protein Info
Gene SymbolLGALS1
Full NameGalectin-1
AliasesLGALS1PROTEIN
Chromosome22q13.1
FunctionLGALS1 performs diverse biological functions:
Amino Acids135 aa
PathwaysMapk
GeneCardsLGALS1
Human Protein AtlasLGALS1
Carbohydrate Recognition Domain (CRD)~130 amino acids for β-galactoside binding
N-terminal RegionInvolved in dimerization
Dimeric FormFunctional unit (homodimer)
Conserved SequenceWXXERXR motif for carbohydrate binding
Associated DiseasesAls, Ms
InteractionsCDK1, EGFR, ERBB2, FOXO1, GENES, GNB4
KG Connections88 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (23)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40
Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.