protein 684 words KG: HSPH1PROTEIN
Contents

HSPH1 Protein

🔬 Protein Info
Gene SymbolHSPH1
Full NameHeat Shock Protein Family H (Hsp110) Member 1
Chromosome14q21.3.
FunctionMember 1), also known as Hsp105 or Hsp110, is a member of the Hsp110 family of heat shock proteins
Primary Expressionvarious cancers
Subcellular Localization</td><td>Cytoplasm, Nucleus</td></tr>
Molecular Weight110 kDa
PathwaysFerroptosis
UniProt IDQ9Y617
NCBI Gene ID10884
Ensembl IDENSG00000120655
OMIM607547
GeneCardsHSPH1
Human Protein AtlasHSPH1
Aggregation preventionSequesters hydrophobic polypeptides
Associated Diseasesneurodegeneration
InteractionsATF2, CANCER, DNAJA1, DNAJB1, FERROPTOSIS, HSC70
KG Connections55 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 3 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 3 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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