| Gene Symbol | HDAC10 |
| Aliases | Histone Deacetylase 10 |
| Chromosome | 22q13.33. |
| Protein Type | Gene |
| Function | is a class IIb histone deacetylase encoded by the HDAC10 gene located on chromosome 22q13. |
| Primary Expression | both neurons and glia, with astrocytic and microglial expression particularly relevant to understanding its role in neuroinflammation |
| Subcellular Localization | . The enzyme contains a zinc-dependent deacetylase domain characteristic of all HDACs, enabling its catalytic function |
| Molecular Weight | 78 kDa |
| Amino Acids | 669 aa |
| Exons | 16 |
| Pathways | Epigenetic |
| GeneCards | HDAC10 |
| Human Protein Atlas | HDAC10 |
| HDAC family proteins | HDAC1, HDAC3, HDAC6 (particularly relevant for autophagy and cytoplasmic function) |
| Autophagy machinery | ULK1, LC3, ATG proteins, p |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | AND, DNMT3A, HDAC1 |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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