protein 659 words KG: GRIA3
Contents

GRIA3 Protein

🔬 Protein Info
Gene SymbolGRIA3
Protein FamilyAMPA receptor family, ionotropic glutamate receptor family
FunctionAMPA receptors containing GluA3 subunits mediate fast excitatory neurotransmission at the vast majority of synapses in the brain.
Subcellular LocalizationPostsynaptic membrane, synapse
Molecular Weight100 kDa
Amino Acids894 aa
Exons22
PathwaysCamp Signaling
UniProt ID[P42263](https://www.uniprot.org/uniprot/P42263)
GeneCardsGRIA3
Human Protein AtlasGRIA3
Associated DiseasesNeurodegeneration
KG Connections37 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (4)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Stress-induced depression model sleep architecture analysis
validation · proposed · Score: 0.90

See Also (10)

Genes
index · KG edge: co_discussed
ACTN2 — Actinin Alpha 2
gene · KG edge: regulates
CLU — Clusterin (Apolipoprotein J)
gene · KG edge: regulates
EGFR — Epidermal Growth Factor Receptor
gene · KG edge: regulates
FHL1 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

KCNMB1 therapeutic_target GRIA3
KCNN2 associated_with GRIA3
GRIA3 therapeutic_target KCNK2
KCNK2 therapeutic_target GRIA3
FHL1 regulates GRIA3
MAPT regulates GRIA3
ACTN2 regulates GRIA3
CLU regulates GRIA3
PDE4D regulates GRIA3
EGFR regulates GRIA3

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