| Gene Symbol | GABRB3 |
| Aliases | GABA-A receptor beta3 subunit |
| Chromosome | 15q12 |
| Protein Type | Receptor |
| Function | is a critical component of many GABA-A receptor subtypes, including the predominant benzodiazepine-sensitive receptors in the thalamus and cortex. |
| Primary Expression | Brain (thalamus, cortex, hippocampus), widespread CNS |
| Subcellular Localization | </strong></td><td>Plasma membrane (postsynaptic)</td></tr> |
| Molecular Weight | 54 kDa |
| Amino Acids | 473 aa |
| UniProt ID | P28472 |
| OMIM | 137192 |
| GeneCards | GABRB3 |
| Human Protein Atlas | GABRB3 |
| Large Extracellular N-terminus | Contains the GABA binding site |
| Four Transmembrane Segments (M1-M4) | Form the channel pore |
| Associated Diseases | neurodegeneration |
| Interactions | A2M, BCHE, CHRFAM7A, CNTN1, DNA, ESR1 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!