protein 549 words KG: FOXA2PROTEIN
Contents

FOXA2 Protein

🔬 Protein Info
Gene SymbolFOXA2
Full NameForkhead Box A2
AliasesFOXA2PROTEIN
Protein TypeTranscription Factor
Functionis a forkhead family transcription factor that plays critical roles in the development and maintenance of dopaminergic neurons in the midbrain.
Molecular Weight48.3 kDa
Amino Acids110 aa
PathwaysAngiogenesis
Ensembl IDENSG00000156413
GeneCardsFOXA2
Human Protein AtlasFOXA2
Forkhead domainA conserved DNA-binding domain of approximately 110 amino acids that recognizes the consensus sequence (G/A)(T/C)(A/C)AA(C/T)A
Transactivation domainLocated at the N-terminus for transcriptional activation
C-terminal domainInvolved in protein-protein interactions
Associated DiseasesALS, Alzheimer, Alzheimer'S Disease, dementia, disease, neurodegeneration
InteractionsDAT, EN1, EN2, FOXO1, FOXO3, INSULIN RESISTANCE
KG Connections77 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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