| Gene Symbol | FAN1 |
| Full Name | FANCD2 Associated Nuclease 1 |
| Chromosome | 15q13.1-q13.3 |
| Function | is a DNA repair nuclease that plays a critical role in interstrand crosslink repair |
| Primary Expression | peripheral tissues |
| Molecular Weight | 86 kDa |
| UniProt ID | Q8IY92 (FAN1) |
| NCBI Gene ID | 22919 |
| Ensembl ID | ENSG00000101391 |
| OMIM | 613375 |
| GeneCards | FAN1 |
| Human Protein Atlas | FAN1 |
| SAP domain (aa 1-70) | DNA binding domain that recognizes specific DNA structures |
| Helix-hairpin-helix domain | Involved in DNA recognition and binding |
| VRR nuclease domain (aa 400-700) | Catalytic center with endonuclease activity |
| Associated Diseases | Als, Huntington, Ms |
| Interactions | DNA, HTT, MSH3, PMS2 |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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