| Gene Symbol | DYRK1B |
| Full Name | Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B |
| Aliases | Dual-specificity Tyrosine-Phosphorylation Regulated Kinase 1B |
| Chromosome | 19p13.12 |
| Protein Type | Kinase |
| Function | encodes a dual-specificity protein kinase belonging to the DYRK family, which phosphorylates substrates on both serine/threonine and tyrosine residues. |
| Primary Expression | the brain and is catalytically active at the time of translation through an intramolecular autophosphorylation mechanism |
| Subcellular Localization | [@ariccacl2019] |
| Molecular Weight | 64.7 kDa |
| Amino Acids | 629 aa |
| Exons | 15 |
| Pathways | Mitochondrial Function |
| UniProt ID | Q9Y463 |
| NCBI Gene ID | 9149 |
| Ensembl ID | ENSG00000105204 |
| OMIM | 604556 |
| GeneCards | DYRK1B |
| Human Protein Atlas | DYRK1B |
| Associated Diseases | neurodegeneration |
| Interactions | ATP, CRBN, DYRK1A, MITOCHONDRIAL DYSFUNCTION, STAT3 |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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