| Gene Symbol | DDX6 |
| Full Name | DEAD-Box Helicase 6 |
| Chromosome | 11p13 |
| Function | is a highly conserved ATP-dependent RNA helicase that plays central roles in RNA metabolism, including mRNA decay, translational repression, and the formation of RNA granules. |
| Primary Expression | the brain with high levels in: - Cortex — pyramidal neurons - Hippocampus — CA1 and CA3 pyramid |
| Molecular Weight | 54 kDa |
| Amino Acids | 482 aa |
| Pathways | Autophagy, Er Stress, Inflammasome |
| UniProt ID | P46193 |
| NCBI Gene ID | 1656 |
| Ensembl ID | ENSG00000110367 |
| OMIM | 601834 |
| GeneCards | DDX6 |
| Human Protein Atlas | DDX6 |
| Associated Diseases | neurodegeneration |
| Interactions | ASC, AUTOPHAGY, INFLAMMATION, NLRP3, P62, SQSTM1 |
| KG Connections | 18 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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