| Gene Symbol | CNR1 |
| Full Name | Cannabinoid Receptor 1 |
| Chromosome | 6q25.2 |
| Function | The CNR1 gene encodes the cannabinoid receptor type 1 (CB1), a G protein-coupled receptor that is the most abundant cannabinoid receptor in the brain. |
| Molecular Weight | 53 kDa |
| Pathways | MAPK pathway |
| UniProt ID | P21554 |
| NCBI Gene ID | 1268 |
| Ensembl ID | ENSG00000118432 |
| OMIM | 114010 |
| GeneCards | CNR1 |
| Human Protein Atlas | CNR1 |
| N-terminal extracellular domain | Contains glycosylation sites and ligand-binding region |
| Seven transmembrane helices | Form the classic GPCR bundle |
| Intracellular loops | Couple to G proteins (Gi/o) |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, depression, neurodegeneration |
| Known Drugs/Compounds | cannabinoids |
| Interactions | AKT, ALZHEIMER, ANXIETY, AR, BDNF, DEPRESSION |
| KG Connections | 220 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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