protein 722 words KG: CIITAPROTEIN
Contents

CIITA Protein

🔬 Protein Info
Gene SymbolCIITA
AliasesCIITAPROTEIN
Chromosome16p13.13
Protein TypeTranscriptional coactivator
Function### MHC Class II Expression
Primary Expressionnon-immune cells: - Endothelial cells: Can express MHC class II in response to IFN-γ - Tumor cells: Sometimes expressed in cancer cells - Ne
Subcellular Localization** | Nucleus |
Molecular Weight125 kDa
Amino Acids1130 aa
PathwaysAutophagy, Immune Response, Inflammasome, Mitophagy
UniProt IDP33076
NCBI Gene ID4261
Ensembl IDENSG00000179583
GeneCardsCIITA
Human Protein AtlasCIITA
Associated Diseasesneurodegeneration
InteractionsAND, CANCER, CD8, CHIP, CREB1, DNA
KG Connections59 knowledge graph edges
DatabasesGeneCardsHPASTRING

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