| Gene Symbol | CERULOPLASMIN |
| Function | Ceruloplasmin is a multi-copper ferroxidase essential for systemic and brain iron metabolism |
| Molecular Weight | 151 kDa |
| Amino Acids | 1046 aa |
| GeneCards | CERULOPLASMIN |
| Human Protein Atlas | CERULOPLASMIN |
| Six copper atoms | Three type I coppers (blue), one type II, two type III |
| Three plastocyanin-like domains | Sixfold internal sequence repeat |
| Iron-binding sites | Multiple sites for substrate Fe2+ binding |
| GPI-anchor site | Alternative C-terminus for membrane attachment in brain |
| Iron efflux from brain | Works with ferroportin to export iron |
| Neuronal iron supply | Generates transferrin-bound iron for neurons |
| Associated Diseases | neurodegeneration |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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