| Gene Symbol | CERS1 (LASS1) |
| Full Name | Ceramide Synthase 1 / Longevity Assurance 1 |
| Chromosome | 19p13.3 |
| Protein Type | Enzyme |
| Function | is a critical enzyme in the biosynthesis of ceramides, a fundamental class of sphingolipids essential for cellular membrane structure and signaling functions. |
| Subcellular Localization | </strong></td><td>Endoplasmic reticulum</td></tr> |
| Molecular Weight | 48 kDa |
| Amino Acids | 422 aa |
| Pathways | Mitophagy |
| UniProt ID | Q8IV08 |
| NCBI Gene ID | 24145 |
| Ensembl ID | ENSG00000154188 |
| OMIM | 606919 |
| Lag1p Domain | Conserved region essential for ceramide synthase activity |
| HOX Domain | Homeobox domain involved in substrate specificity |
| Associated Diseases | neurodegeneration |
| Interactions | PINK1 |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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