| Gene Symbol | CACNA1I |
| Full Name | CACNA1I - Calcium Voltage-Gated Channel Subunit Alpha1 I |
| Aliases | Page for CACNA1I Gene, Page for CACNA1I Protein |
| Chromosome | 22q12.3 |
| Protein Type | Gene |
| Function | Cav3.3 (T-type) calcium channels are crucial for |
| Amino Acids | 226 aa |
| GeneCards | CACNA1I |
| Human Protein Atlas | CACNA1I |
| Transmembrane domains | 10 segments arranged in 4 repeats |
| Voltage sensor | S4 segment in each repeat with positively charged residues |
| Pore region | Forms ion selectivity filter between S5 and S6 |
| Cytoplasmic termini | N- and C-termini contain regulatory domains |
| Domain I | Contains the main voltage-sensing component |
| Domain II | Links to domain I and contributes to channel gating |
| Associated Diseases | neurodegeneration |
| Interactions | CACNA1A, CACNA1C, CACNA1D, CACNA1E, cacna1f, CACNA1F |
| KG Connections | 39 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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